Experiment Overview

Repository ID: FR-FCM-Z5Z8 Experiment name: Analysis of TC-mAb mice (Exp1: early B cell development) MIFlowCyt score: 31.13%
Primary researcher: Takashi Moriwaki PI/manager: Yasuhiro Kazuki Uploaded by: Takashi Moriwaki
Experiment dates: 2019-08-05 - 2019-12-19 Dataset uploaded: Feb 2022 Last updated: Mar 2022
Keywords: None Manuscripts:
Organizations: Tottori University, Yonago, (Japan)
Purpose: The experiment had been performed to analyze early B cell development of human antibody-procducing mice (TC-mAb mice). The flow cytometry experiment was designed to detect the subsets of Pro-B/ Pre-B (IgM-B220+), immature B (IgM+B220+), and mature recirculating B (IgMlo/+B220hi) cells in bone marrow.
Conclusion: None
Comments: This experiment corresponds to Figure 7a and Supplementary Figure 15-16 in the paper "Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci". Publication link:
Funding: Not disclosed
Quality control: None
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