Experiment Overview
| Repository ID: | FR-FCM-ZYKP | Experiment name: | Predictive Biomarkers for Response to Anti-CTLA-4 and Anti-PD-1 Immunotherapy | MIFlowCyt score: | 84.00% |
| Primary researcher: | Priyanka Balasubrahmanyam | PI/manager: | Holden Maecker | Uploaded by: | Priyanka Balasubrahmanyam |
| Experiment dates: | 2018-05-30 - 2018-05-30 | Dataset uploaded: | May 2018 | Last updated: | Apr 2019 |
| Keywords: | [CyTOF] [immunotherapy] [biomarker] | Manuscripts: | [29510697] | ||
| Organizations: |
Stanford University, Microbiology and Immunology, Stanford, CA (USA)
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| Purpose: | Distinct predictive biomarker candidates for response to anti-CTLA-4 and anti-PD-1 immunotherapy in melanoma patients | ||||
| Conclusion: | Distinct predictive biomarker candidates identified for the 2 therapies. | ||||
| Comments: | None | ||||
| Funding: | Not disclosed | ||||
| Quality control: | EQ Calibration Beads from Fluidigm used. Normalization of .fcs files using the Nolab Lab Matlab-based normalizer. | ||||
Experiment variables
| Conditions | |
|---|---|
| · Unstimulated | 039-US_01_normalized.fcs · 103-US_01_normalized.fcs · 162-US_01_normalized.fcs · 191-US_01_normalized.fcs · 203-US_01_normalized.fcs · 246-US_01_normalized.fcs · 266_US_01_normalized.fcs · 343-US_01_normalized.fcs · 346-US_01_normalized.fcs · 598-US_01_normalized.fcs · 632-US_01_normalized.fcs · 669-US_01_normalized.fcs · 685-US_01_normalized.fcs · 710_US_01_normalized.fcs · 711_US_01_normalized.fcs · 830-US_01_normalized.fcs · 834-US_01_normalized.fcs · 843-US_01_normalized.fcs · 883_US_01-concat_normalized.fcs · 906-US_01_normalized.fcs · 923-2-US_01_normalized.fcs · 929-US_01-concat_normalized.fcs · 961-US_01_normalized.fcs · 999-US_01_normalized.fcs · 000-US_01_normalized.fcs · 023-US_01_normalized.fcs · 097-US_01_normalized.fcs · 146-US_cct_normalized.fcs · 165-US_01_normalized.fcs · 240-US_cct_normalized.fcs · 257-US_cct_normalized.fcs · 287-US_01_normalized.fcs · 353-US_cct_normalized.fcs · 359-US_cct_normalized.fcs · 371-US_01_normalized.fcs · 427-US_01_normalized.fcs · 441-US_01_normalized.fcs · 475-US_cct_normalized.fcs · 489-US_01_normalized.fcs · 531-US_01_normalized.fcs · 690-US_cct_normalized.fcs · 701-US_03_normalized.fcs · 702-US_01_normalized.fcs · 712-US_01_normalized.fcs · 748-US_cct_normalized.fcs · 754-US_01_normalized.fcs · 809-US_01_normalized.fcs · 893-US_01_normalized.fcs · 906-US_cct_normalized.fcs · C334-US_01_normalized.fcs · C335-US_01_normalized.fcs · C351-US_01_normalized.fcs · C360-US_01_normalized.fcs · C374-US_cct_normalized.fcs · C392-US_cct_normalized.fcs · C394-US_01_normalized.fcs · C403-US_01_normalized.fcs · C412-US_01_normalized.fcs · C493-US_01_normalized.fcs · C504-US_01_normalized.fcs · C56-US_01_normalized.fcs · P239-US_cct_normalized.fcs · P245-US_01_normalized.fcs · P262-US_cct_normalized.fcs |
| · PMA+Ionomycin | 039-PMA_Iono_01_normalized.fcs · 103-PMA_Iono_01_normalized.fcs · 162-PMA_Iono_01-concat_normalized.fcs · 191-PMA_Iono_01-concat_normalized.fcs · 203-PMA_Iono_01_normalized.fcs · 246-PMA_Iono_01_normalized.fcs · 266_PMA_Iono_01_normalized.fcs · 343-PMA_Iono_02_normalized.fcs · 346-PMA_Iono_01_normalized.fcs · 598-PMA_Iono_01_normalized.fcs · 632-PMA_Iono_01-concat_normalized.fcs · 669-PMA_Iono_01_normalized.fcs · 685-PMA_Iono_01_normalized.fcs · 710_PMA_Iono_01_normalized.fcs · 711_PMA_Iono_01_normalized.fcs · 830-PMA_Iono_01_normalized.fcs · 834-PMA_Iono_01_normalized.fcs · 843-PMA_Iono_02_normalized.fcs · 883_PMA_Iono_01_normalized.fcs · 906-PMA_Iono_01_normalized.fcs · 923-2-PMA_Iono_01_normalized.fcs · 929-PMA_Iono_01_normalized.fcs · 961-PMA_Iono_01_normalized.fcs · 999-PMA_Iono_01_normalized.fcs · 000-PMA_Iono_01_normalized.fcs · 023-PMA_Iono_01_normalized.fcs · 097-PMA_Iono_01_normalized.fcs · 146-PMA_Iono_cct_normalized.fcs · 165-PMA_Iono_01_normalized.fcs · 240-PMA_Iono_cct_normalized.fcs · 257-PMA_Iono_01_normalized.fcs · 287-PMA_Iono_01_normalized.fcs · 353-PMA_Iono_01_normalized.fcs · 359-PMA_Iono_cct_normalized.fcs · 371-PMA_Iono_cct_normalized.fcs · 427-PMA_Iono_01_normalized.fcs · 441-PMA_Iono_cct_normalized.fcs · 475-PMA_Iono_01_normalized.fcs · 489-PMA_Iono_01_normalized.fcs · 531-PMA_Iono_01_normalized.fcs · 690-PMA_Iono_cct_normalized.fcs · 701-PMA_Iono_01_normalized.fcs · 702-PMA_Iono_01_normalized.fcs · 712-PMA_Iono_01_normalized.fcs · 748-PMA_Iono_cct_normalized.fcs · 754-PMA_Iono_cct_normalized.fcs · 809-PMA_Iono_01_normalized.fcs · 893-PMA_Iono_01_normalized.fcs · 906-PMA_Iono_cct_normalized.fcs · C334-PMA_01_normalized.fcs · C335-PMA_01_normalized.fcs · C351-PMA_01_normalized.fcs · C360-PMA_01_normalized.fcs · C374-PMA_01_normalized.fcs · C392-PMA_cct_normalized.fcs · C394-PMA_01_normalized.fcs · C403-PMA_01_normalized.fcs · C412-PMA_01_normalized.fcs · C493-PMA_01_normalized.fcs · C504-PMA_01_normalized.fcs · C56-PMA_01_normalized.fcs · P239-PMA_cct_normalized.fcs · P245-PMA_cct_normalized.fcs · P262-PMA_01_normalized.fcs |
| Timepoints | |
|---|---|
| · Pre-treatment | 039-PMA_Iono_01_normalized.fcs · 039-US_01_normalized.fcs · 103-PMA_Iono_01_normalized.fcs · 103-US_01_normalized.fcs · 162-PMA_Iono_01-concat_normalized.fcs · 162-US_01_normalized.fcs · 191-PMA_Iono_01-concat_normalized.fcs · 191-US_01_normalized.fcs · 203-PMA_Iono_01_normalized.fcs · 203-US_01_normalized.fcs · 246-PMA_Iono_01_normalized.fcs · 246-US_01_normalized.fcs · 266_PMA_Iono_01_normalized.fcs · 266_US_01_normalized.fcs · 343-PMA_Iono_02_normalized.fcs · 343-US_01_normalized.fcs · 346-PMA_Iono_01_normalized.fcs · 346-US_01_normalized.fcs · 598-PMA_Iono_01_normalized.fcs · 598-US_01_normalized.fcs · 632-PMA_Iono_01-concat_normalized.fcs · 632-US_01_normalized.fcs · 669-PMA_Iono_01_normalized.fcs · 669-US_01_normalized.fcs · 685-PMA_Iono_01_normalized.fcs · 685-US_01_normalized.fcs · 710_PMA_Iono_01_normalized.fcs · 710_US_01_normalized.fcs · 711_PMA_Iono_01_normalized.fcs · 711_US_01_normalized.fcs · 830-PMA_Iono_01_normalized.fcs · 830-US_01_normalized.fcs · 834-PMA_Iono_01_normalized.fcs · 834-US_01_normalized.fcs · 843-PMA_Iono_02_normalized.fcs · 843-US_01_normalized.fcs · 883_PMA_Iono_01_normalized.fcs · 883_US_01-concat_normalized.fcs · 906-PMA_Iono_01_normalized.fcs · 906-US_01_normalized.fcs · 923-2-PMA_Iono_01_normalized.fcs · 923-2-US_01_normalized.fcs · 929-PMA_Iono_01_normalized.fcs · 929-US_01-concat_normalized.fcs · 961-PMA_Iono_01_normalized.fcs · 961-US_01_normalized.fcs · 999-PMA_Iono_01_normalized.fcs · 999-US_01_normalized.fcs · 000-PMA_Iono_01_normalized.fcs · 000-US_01_normalized.fcs · 023-PMA_Iono_01_normalized.fcs · 023-US_01_normalized.fcs · 097-PMA_Iono_01_normalized.fcs · 097-US_01_normalized.fcs · 146-PMA_Iono_cct_normalized.fcs · 146-US_cct_normalized.fcs · 165-PMA_Iono_01_normalized.fcs · 165-US_01_normalized.fcs · 240-PMA_Iono_cct_normalized.fcs · 240-US_cct_normalized.fcs · 257-PMA_Iono_01_normalized.fcs · 257-US_cct_normalized.fcs · 287-PMA_Iono_01_normalized.fcs · 287-US_01_normalized.fcs · 353-PMA_Iono_01_normalized.fcs · 353-US_cct_normalized.fcs · 359-PMA_Iono_cct_normalized.fcs · 359-US_cct_normalized.fcs · 371-PMA_Iono_cct_normalized.fcs · 371-US_01_normalized.fcs · 427-PMA_Iono_01_normalized.fcs · 427-US_01_normalized.fcs · 441-PMA_Iono_cct_normalized.fcs · 441-US_01_normalized.fcs · 475-PMA_Iono_01_normalized.fcs · 475-US_cct_normalized.fcs · 489-PMA_Iono_01_normalized.fcs · 489-US_01_normalized.fcs · 531-PMA_Iono_01_normalized.fcs · 531-US_01_normalized.fcs · 690-PMA_Iono_cct_normalized.fcs · 690-US_cct_normalized.fcs · 701-PMA_Iono_01_normalized.fcs · 701-US_03_normalized.fcs · 702-PMA_Iono_01_normalized.fcs · 702-US_01_normalized.fcs · 712-PMA_Iono_01_normalized.fcs · 712-US_01_normalized.fcs · 748-PMA_Iono_cct_normalized.fcs · 748-US_cct_normalized.fcs · 754-PMA_Iono_cct_normalized.fcs · 754-US_01_normalized.fcs · 809-PMA_Iono_01_normalized.fcs · 809-US_01_normalized.fcs · 893-PMA_Iono_01_normalized.fcs · 893-US_01_normalized.fcs · 906-PMA_Iono_cct_normalized.fcs · 906-US_cct_normalized.fcs · C334-PMA_01_normalized.fcs · C334-US_01_normalized.fcs · C335-PMA_01_normalized.fcs · C335-US_01_normalized.fcs · C351-PMA_01_normalized.fcs · C351-US_01_normalized.fcs · C360-PMA_01_normalized.fcs · C360-US_01_normalized.fcs · C374-PMA_01_normalized.fcs · C374-US_cct_normalized.fcs · C392-PMA_cct_normalized.fcs · C392-US_cct_normalized.fcs · C394-PMA_01_normalized.fcs · C394-US_01_normalized.fcs · C403-PMA_01_normalized.fcs · C403-US_01_normalized.fcs · C412-PMA_01_normalized.fcs · C412-US_01_normalized.fcs · C493-PMA_01_normalized.fcs · C493-US_01_normalized.fcs · C504-PMA_01_normalized.fcs · C504-US_01_normalized.fcs · C56-PMA_01_normalized.fcs · C56-US_01_normalized.fcs · P239-PMA_cct_normalized.fcs · P239-US_cct_normalized.fcs · P245-PMA_cct_normalized.fcs · P245-US_01_normalized.fcs · P262-PMA_01_normalized.fcs · P262-US_cct_normalized.fcs |
