Experiment Overview
| Repository ID: | FR-FCM-Z2MJ | Experiment name: | MC38 TILs anti-Gal9/GITR | MIFlowCyt score: | 58.76% |
| Primary researcher: | Riyao Yang | PI/manager: | Riyao Yang | Uploaded by: | Riyao Yang |
| Experiment dates: | 2019-05-30 - | Dataset uploaded: | May 2020 | Last updated: | Dec 2020 |
| Keywords: | [immunotherapy] [TIL] [galectin-9] [GITR] | Manuscripts: | |||
| Organizations: |
The University of Texas MD Anderson Cancer Center, Houston, Texas (USA)
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| Purpose: | To identify tumor infiltrating immune cell subsets underlying response to anti-Gal-9/GITR immunotherapy | ||||
| Conclusion: | Gal-9 inhibition expands Treg cells and a subset of CD8 T cells. Combination of anti-Gal-9 with GITR agonism further expands CD8 T cells and deplete Treg cells. | ||||
| Comments: | None | ||||
| Funding: | Not disclosed | ||||
| Quality control: | None | ||||
Experiment variables
| Conditions | |
|---|---|
| · Control | Control_1.fcs · Control_2.fcs · Control_3.fcs · Control_4.fcs |
| · anti-Gal-9 | anti-Gal-9_1.fcs · anti-Gal-9_2.fcs · anti-Gal-9_3.fcs · anti-Gal-9_4.fcs |
| · anti-GITR | anti-GITR_1.fcs · anti-GITR_2.fcs · anti-GITR_3.fcs · anti-GITR_4.fcs |
| · Combo | Combo_1.fcs · Combo_2.fcs · Combo_3.fcs · Combo_4.fcs |
| Sample Type | |
|---|---|
| · Control | Control_1.fcs · Control_2.fcs · Control_3.fcs · Control_4.fcs |
| · anti-Gal-9 | anti-Gal-9_1.fcs · anti-Gal-9_2.fcs · anti-Gal-9_3.fcs · anti-Gal-9_4.fcs |
| · anti-GITR | anti-GITR_1.fcs · anti-GITR_2.fcs · anti-GITR_3.fcs · anti-GITR_4.fcs |
| · Combo | Combo_1.fcs · Combo_2.fcs · Combo_3.fcs · Combo_4.fcs |
