Notice: Temporary Suspension of New Experiment Creation
We have temporarily disabled the creation of new experiments as we are continuously running out of space. This issue has been impacting both uploads and downloads from FlowRepository. By taking this step, we aim to make downloads of existing data more reliable.
We apologize for the inconvenience and appreciate your understanding as we work on upgrading our hardware and improving the overall solution.
Thank you for your patience.

Download-button_s

Experiment Overview

Repository ID: FR-FCM-Z3PM Experiment name: Cell isolation by FACS of protein coding genes targeted with pgRNAs along BLaER1 transdifferentiation MIFlowCyt score: 98.00%
Primary researcher: Carme Arnan PI/manager: Carme Arnan Uploaded by: Carme Arnan
Experiment dates: 2019-05-03 - 2019-06-14 Dataset uploaded: Apr 2021 Last updated: May 2022
Keywords: [macrophages] [pre-B cells] [BLaER-Cas9 transdiferentiation] [FURIN] [NFE2] Manuscripts:
Organizations: Cytometry Unit Facility (CRG/UPF), Barcelona, Catalonia (SPAIN)
Purpose: Validate the effect of knocking out protein coding genes FURIN and NFE2 in the transdifferentiation of BLaER-Cas9 cells.
Conclusion: FURIN and NFE2 knockout could be further validated at RNA level (RT-qPCR) and protein level (western blot) from sorted cells.
Comments: None
Funding: N/A
Quality control: BLaER-Cas9 cells infected with intergenic pgRNAs.


Experiment variables

Timepoints
· T0 20190503_4 Scramble T0.fcs · 20190503_6 Furin T0.fcs · 20190506_5 Scamble T0.fcs · 20190506_7 NFE2 T0.fcs · 20190614_10 NFE T0.fcs · 20190614_5 Scramble T0.fcs · 20190614_8 Furin T0.fcs
· T2 20190506_6 Scamble T2.fcs · 20190506_8 NFE2 T2.fcs · 20190614_6 Scramble T2.fcs · 20190614_11 NFE T2.fcs
· T3 20190503_5 Scramble T3.fcs · 20190503_7 Furin T3.fcs · 20190614_7 Scramble T3.fcs · 20190614_9 Furin T3.fcs

Conditions
· Controls 20190503_4 Scramble T0.fcs · 20190503_5 Scramble T3.fcs · 20190506_5 Scamble T0.fcs · 20190506_6 Scamble T2.fcs · 20190614_5 Scramble T0.fcs · 20190614_6 Scramble T2.fcs · 20190614_7 Scramble T3.fcs
· Samples 20190503_6 Furin T0.fcs · 20190503_7 Furin T3.fcs · 20190506_7 NFE2 T0.fcs · 20190506_8 NFE2 T2.fcs · 20190614_10 NFE T0.fcs · 20190614_8 Furin T0.fcs · 20190614_9 Furin T3.fcs · 20190614_11 NFE T2.fcs

Sample Type
· R1 20190503_4 Scramble T0.fcs · 20190503_5 Scramble T3.fcs · 20190503_6 Furin T0.fcs · 20190503_7 Furin T3.fcs · 20190506_6 Scamble T2.fcs · 20190506_7 NFE2 T0.fcs · 20190506_8 NFE2 T2.fcs
· R2 20190506_5 Scamble T0.fcs · 20190614_10 NFE T0.fcs · 20190614_5 Scramble T0.fcs · 20190614_6 Scramble T2.fcs · 20190614_7 Scramble T3.fcs · 20190614_8 Furin T0.fcs · 20190614_9 Furin T3.fcs · 20190614_11 NFE T2.fcs

Download FCS Files or login and see the dataset in your inbox for further annotation details.