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Experiment Overview

Repository ID: FR-FCM-Z47G Experiment name: Tetramer staining HLA E MIFlowCyt score: 29.51%
Primary researcher: Krista van Meijgaarden PI/manager: Krista van Meijgaarden Uploaded by: krista van Meijgaarden
Experiment dates: 2014-04-01 - 2016-12-31 Dataset uploaded: Jul 2021 Last updated: Aug 2021
Keywords: [CD8 T-cells] [tetramer] [HLA-E] [TB] Manuscripts: [25631937] [PMC25631937]
Organizations: Central Laboratory for Advanced Diagnostic and Biomedical Research (CLADIBIOR), Università di Palermo, Dipartimento di Biopatologia e Biotecnologie Mediche e Forensi, Palermo, (Italy)
Purpose: screening for HLA E responses in tuberculosis patients vs latently infected individuals
Conclusion: the ex vivo frequency of tetramer-specific CD8 T cells was higher in TB patients than in latent tuberculosis infection (LTBI) subjects and this difference attained statistical significance with all epitopes
Comments: a few FMO controls for the tetramer staining are included in this dataset. All other FMO controls for the tetramer stainings are available upon request
Funding: This work was supported by grants from the European Commission within the 6th Framework Programme, TB-VAC contract no. LSHP-CT-2003-503367, and the 7th Framework Programme, NEWTBVAC contract no. HEALTH-F3-2009-241745
Quality control: FMO controls are available for all indivduals tested
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