
Experiment Overview
Repository ID: | FR-FCM-Z47G | Experiment name: | Tetramer staining HLA E | MIFlowCyt score: | 29.51% |
Primary researcher: | Krista van Meijgaarden | PI/manager: | Krista van Meijgaarden | Uploaded by: | krista van Meijgaarden |
Experiment dates: | 2014-04-01 - 2016-12-31 | Dataset uploaded: | Jul 2021 | Last updated: | Aug 2021 |
Keywords: | [CD8 T-cells] [tetramer] [HLA-E] [TB] | Manuscripts: | [25631937] [PMC25631937] | ||
Organizations: |
Central Laboratory for Advanced Diagnostic and Biomedical Research (CLADIBIOR), Università di Palermo, Dipartimento di Biopatologia e Biotecnologie Mediche e Forensi, Palermo, (Italy)
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Purpose: | screening for HLA E responses in tuberculosis patients vs latently infected individuals | ||||
Conclusion: | the ex vivo frequency of tetramer-specific CD8 T cells was higher in TB patients than in latent tuberculosis infection (LTBI) subjects and this difference attained statistical significance with all epitopes | ||||
Comments: | a few FMO controls for the tetramer staining are included in this dataset. All other FMO controls for the tetramer stainings are available upon request | ||||
Funding: | This work was supported by grants from the European Commission within the 6th Framework Programme, TB-VAC contract no. LSHP-CT-2003-503367, and the 7th Framework Programme, NEWTBVAC contract no. HEALTH-F3-2009-241745 | ||||
Quality control: | FMO controls are available for all indivduals tested |