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Experiment Overview

Repository ID: FR-FCM-Z5MZ Experiment name: Mouse neutrophil degranulation MIFlowCyt score: 53.75%
Primary researcher: Shuang Peng PI/manager: Shuang Peng Uploaded by: Shuang Peng
Experiment dates: 2017-10-02 - 2022-05-30 Dataset uploaded: Aug 2022 Last updated: Aug 2022
Keywords: [CD63] [degranulation] [Mouse neutrophil] Manuscripts:
Organizations: The University of Bern, Bern, (Switzerland)
Purpose: To examine mouse neutrophil degranulation by measuring cell surface expression of CD63.
Conclusion: RhoH incuction by GM-CSF or RhoH overexpression impaired neutrophil degranulation.
Comments: None
Funding: Not disclosed
Quality control: PE-conjugated Rat IgG2a, κ isotype control (clone R35-95; BD Biosciences) was used at the same concentration.


Experiment variables

Sample Type
· BM neutrophils IgG GM 20 min+C5a.fcs · IgG GM 3h+C5a.fcs · Isotype GM20 +c5a.fcs · Isotype GM3h +C5a.fcs · Isotype control GM 20 min+C5a.fcs · Isotype control GM 3h+C5a.fcs · KO 10.fcs · KO 20.fcs · KO Control.fcs · KO Control.fcs-(1) · KO GM + c5a.fcs · KO GM 180 min +C5a.fcs · KO GM 20 min +C5a.fcs · KO GM 20min+C5a.fcs · KO GM 3h +C5a.fcs · KO GM 3h +c5a.fcs · KO GM 3h.fcs · KO GM+C5a.fcs · KO GM+C5a.fcs-(1) · KO PMA.fcs · KO PMA.fcs-(1) · KO control.fcs · KO control.fcs-(1) · KO medium.fcs · KO unstimulated.fcs · Mice KO Control.fcs · Mice KO GM+C5a.fcs · Mice KO PMA.fcs · Mice WT GM+C5a.fcs · Mice WT PMA.fcs · Mice WT control.fcs · RhoH-_- GM+C5a.fcs · RhoH-_- PMA.fcs · RhoH-_- control .fcs · Tube_001.fcs · Tube_002.fcs · Tube_003.fcs · Tube_004.fcs · Tube_005.fcs · Tube_006.fcs · Vector control .fcs · WT 10.fcs · WT 20.fcs · WT Control.fcs · WT Control.fcs-(1) · WT GM + C5a.fcs · WT GM 180 min +C5a.fcs · WT GM 20 min +C5a.fcs · WT GM 3h + C5a.fcs · WT GM 3h+C5a.fcs · WT GM 3h.fcs · WT GM+C5a.fcs · WT GM+C5a.fcs-(1) · WT PMA.fcs · WT PMA.fcs-(1) · WT control.fcs · WT control.fcs-(1) · WT medium.fcs · WT unstimulated.fcs · unstained.fcs
· Hoxb8 neutrophils GM+C5a IgG Hoxb8.fcs · GM+C5a.fcs · HA-RhoH control .fcs · HA-RhoH Control .fcs · HA-RhoH GM+C5a.fcs · HA-RhoH GM+C5a.fcs-(1) · HA-RhoH PMA.fcs · HA-RhoH PMA.fcs-(1) · HA-RhoH unstimulated.fcs · IgG Hoxb8 GM+C5a.fcs · IgG Hoxb8 PMA.fcs · IgG Hoxb8 unstimulated.fcs · IgG control GM+C5a.fcs · IgG control PMA.fcs · IgG control unstimulated.fcs · IgG unstimulated.fcs · Isotype contol unstimulated.fcs · Isotype control.fcs · KO+RhoH GM+C5a.fcs · KO+RhoH PMA.fcs · KO+RhoH unstimulated.fcs · PMA IgG Hoxb8 .fcs · PMA.fcs · Vector GM+C5a.fcs · Vector PMA.fcs · unstimulated IgG Hoxb8.fcs · unstimulated.fcs

Individuals
· isotype control GM+C5a IgG Hoxb8.fcs · IgG GM 20 min+C5a.fcs · IgG GM 3h+C5a.fcs · IgG Hoxb8 GM+C5a.fcs · IgG Hoxb8 PMA.fcs · IgG Hoxb8 unstimulated.fcs · IgG control GM+C5a.fcs · IgG control PMA.fcs · IgG control unstimulated.fcs · IgG unstimulated.fcs · Isotype GM20 +c5a.fcs · Isotype GM3h +C5a.fcs · Isotype contol unstimulated.fcs · Isotype control GM 20 min+C5a.fcs · Isotype control GM 3h+C5a.fcs · Isotype control.fcs · PMA IgG Hoxb8 .fcs · unstained.fcs · unstimulated IgG Hoxb8.fcs
· control HA-RhoH control .fcs · HA-RhoH Control .fcs · HA-RhoH unstimulated.fcs · KO Control.fcs · KO Control.fcs-(1) · KO control.fcs · KO control.fcs-(1) · KO medium.fcs · KO unstimulated.fcs · KO+RhoH unstimulated.fcs · Mice KO Control.fcs · Mice WT control.fcs · RhoH-_- control .fcs · Tube_001.fcs · Tube_004.fcs · Vector control .fcs · WT Control.fcs · WT Control.fcs-(1) · WT control.fcs · WT control.fcs-(1) · WT medium.fcs · WT unstimulated.fcs · unstimulated.fcs
· activated GM+C5a.fcs · HA-RhoH GM+C5a.fcs · HA-RhoH GM+C5a.fcs-(1) · HA-RhoH PMA.fcs · HA-RhoH PMA.fcs-(1) · KO 10.fcs · KO 20.fcs · KO GM + c5a.fcs · KO GM 180 min +C5a.fcs · KO GM 20 min +C5a.fcs · KO GM 20min+C5a.fcs · KO GM 3h +C5a.fcs · KO GM 3h +c5a.fcs · KO GM 3h.fcs · KO GM+C5a.fcs · KO GM+C5a.fcs-(1) · KO PMA.fcs · KO PMA.fcs-(1) · KO+RhoH GM+C5a.fcs · KO+RhoH PMA.fcs · Mice KO GM+C5a.fcs · Mice KO PMA.fcs · Mice WT GM+C5a.fcs · Mice WT PMA.fcs · PMA.fcs · RhoH-_- GM+C5a.fcs · RhoH-_- PMA.fcs · Tube_002.fcs · Tube_003.fcs · Tube_005.fcs · Tube_006.fcs · Vector GM+C5a.fcs · Vector PMA.fcs · WT 10.fcs · WT 20.fcs · WT GM + C5a.fcs · WT GM 180 min +C5a.fcs · WT GM 20 min +C5a.fcs · WT GM 3h + C5a.fcs · WT GM 3h+C5a.fcs · WT GM 3h.fcs · WT GM+C5a.fcs · WT GM+C5a.fcs-(1) · WT PMA.fcs · WT PMA.fcs-(1)

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