Notice: Temporary Suspension of New Experiment Creation
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Experiment Overview

Repository ID: FR-FCM-Z625 Experiment name: Studying the heterogeneity of CAR-NK cells and their in vivo evolution after adoptive transfer from Mass cytometry profiling MIFlowCyt score: 21.00%
Primary researcher: Katy Rezvani PI/manager: Katy Rezvani Uploaded by: Katy Rezvani
Experiment dates: 2018-06-30 - 2022-11-30 Dataset uploaded: Jan 2023 Last updated: Jan 2023
Keywords: [NK cells] [CAR NK] [integration] Manuscripts:
Organizations: None
Purpose: Chimeric antigen receptor (CAR) engineering of natural killer (NK) cells is promising with early- phase clinical studies showing encouraging responses. However, the transcriptional signatures that control the fate of CAR-NK cells after infusion and factors that influence tumor control remain poorly understood. We performed single-cell mass cytometry to study the heterogeneity of CAR-NK cells and their in vivo evolution after adoptive transfer, from the phase of tumor control to relapse.
Conclusion: None
Comments: None
Funding: Not disclosed
Quality control: None
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