Experiment Overview
| Repository ID: | FR-FCM-Z662 | Experiment name: | Immune phenotype associated with SARS-CoV-2 response in solid organ transplanted patients | MIFlowCyt score: | 99.89% |
| Primary researcher: | Stephanie Humblet-Baron | PI/manager: | Stephanie Humblet-Baron | Uploaded by: | Julika Neumann |
| Experiment dates: | 2021-12-10 - 2021-12-16 | Dataset uploaded: | Mar 2023 | Last updated: | Sep 2023 |
| Keywords: | [Transplantation] [SARS-CoV-2] [mRNA Vaccination] | Manuscripts: | |||
| Organizations: |
KU Leuven, Leuven, Vlaams Brabant (Belgium)
|
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| Purpose: | Analysis of baseline PBMC immune phenotype in solid organ transplanted patients and its association with SARS-CoV-2 vaccine response | ||||
| Conclusion: | Distinct immune signatures are associated with a partial and full response to SARS-CoV-2 mRNA vaccination in solid organ transplanted patients that are not necessarily linked to a healthy immune signature | ||||
| Comments: | None | ||||
| Funding: | Not disclosed | ||||
| Quality control: | Healthy and internal controls were included in each experiment | ||||
Experiment variables
| Individuals | |
|---|---|
| · Kidney transplant | Samples_Kidney_Tx_n_011_016_live cells.fcs · Samples_Kidney_Tx_n_043_003_live cells.fcs · Samples_Kidney_Tx_n_044_004_live cells.fcs · Samples_Kidney_Tx_n_045_005_live cells.fcs · Samples_Kidney_Tx_n_050_008_live cells.fcs · Samples_Kidney_Tx_n_052_009_live cells.fcs · Samples_Kidney_Tx_n_053_010_live cells.fcs · Samples_Kidney_Tx_n_061_019_live cells.fcs · Samples_Kidney_Tx_n_067_022_live cells.fcs · Samples_Kidney_Tx_n_077_015_live cells.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_011_016_016_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_042_002_002_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_043_003_003_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_044_004_004_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_045_005_005_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_047_006_006_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_049_007_007_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_052_009_009_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_053_010_010_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_059_018_018_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_061_019_019_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_065_012_012_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_066_021_021_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_066_022_022_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_073_013_013_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_075_014_014_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_075_015_015_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_016_037_130_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_017_021_114_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_019_022_115_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_020_023_116_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_021_024_117_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_023_038_131_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_025_030_123_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_026_004_097_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_028_005_098_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_030_006_099_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_031_007_100_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_033_008_101_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_034_009_102_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_035_010_103_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_036_011_104_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_040_013_106_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_080_019_112_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_101_029_122_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_191_035_128_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_199_031_124_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_201_020_113_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_203_028_121_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_037_036_129_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_038_012_105_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_039_026_119_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_048_032_125_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_051_014_107_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_054_015_108_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_058_027_120_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_060_003_096_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_063_033_126_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_068_001_094_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_069_034_127_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_071_002_095_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_074_016_109_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_078_017_110_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_079_018_111_Live.fcs |
| · Lung transplant | Samples_Lung_049_D1_D0_023_live cells.fcs · Samples_Lung_050_D1_D0_024_live cells.fcs · Samples_Lung_051_D1_D0_025_live cells.fcs · Samples_Lung_053_D1_D0_026_live cells.fcs · Samples_Lung_054_D1_D0_027_live cells.fcs · Samples_Lung_055_D1_D0_028_live cells.fcs · Samples_Lung_056_D1_D0_029_live cells.fcs · Samples_Lung_058_D1_D0_030_live cells.fcs · Samples_Lung_060_D1_D0_032_live cells.fcs · VaccTranspl_ST2_20211210_TP_Lung_049_D1D0_023_023_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_050_D1D0_024_024_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_051_D1D0_025_025_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_053_D1D0_026_026_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_054_D1D0_027_027_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_055_D1D0_028_028_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_056_D1D0_029_029_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_058_D1D0_030_030_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_059_D1D0_031_031_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_060_D1D0_032_032_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_013_D1D0_039_132_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_014_D1D0_040_133_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_015_D1D0_041_134_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_016_D1D0_042_135_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_017_D1D0_043_136_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_018_D1D0_044_137_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_019_D1D0_045_138_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_020_D1D0_046_139_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_021_D1D0_047_140_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_022_D1D0_048_141_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_023_D1D0_049_142_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_024_D1D0_050_143_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_025_D1D0_051_144_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_026_D1D0_052_145_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_027_D1D0_053_146_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_028_D1D0_054_147_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_029_D1D0_055_148_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_030_D1D0_056_149_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_047_D1D0_059_152_Live.fcs |
| · Healthy | Samples_ICOV_267_033_live cells.fcs · Samples_ICOV_304_034_live cells.fcs · Samples_ICOV_310_035_live cells.fcs · Samples_ICOV_374_036_live cells.fcs · Samples_ICOV_423_037_live cells.fcs · Samples_ICOV_460_038_live cells.fcs · Samples_ICOV_496_039_live cells.fcs · VaccTranspl_ST2_20211210_TP_ICOV_267_033_033_Live.fcs · VaccTranspl_ST2_20211210_TP_ICOV_304_034_034_Live.fcs · VaccTranspl_ST2_20211210_TP_ICOV_310_035_035_Live.fcs · VaccTranspl_ST2_20211210_TP_ICOV_374_036_036_Live.fcs · VaccTranspl_ST2_20211210_TP_ICOV_423_037_037_Live.fcs · VaccTranspl_ST2_20211210_TP_ICOV_460_038_038_Live.fcs · VaccTranspl_ST2_20211210_TP_ICOV_469_039_039_Live.fcs · VaccTranspl_ST2_20211216_TP_ICOV_009_060_153_Live.fcs · VaccTranspl_ST2_20211216_TP_ICOV_010_061_154_Live.fcs · VaccTranspl_ST2_20211216_TP_ICOV_012_062_155_Live.fcs · VaccTranspl_ST2_20211216_TP_ICOV_018_063_156_Live.fcs · VaccTranspl_ST2_20211216_TP_ICOV_070_065_158_Live.fcs · VaccTranspl_ST2_20211216_TP_ICOV_177_067_160_Live.fcs · VaccTranspl_ST2_20211216_TP_ICOV_183_068_161_Live.fcs · VaccTranspl_ST2_20211216_TP_ICOV_184_069_162_Live.fcs · VaccTranspl_ST2_20211216_TP_ICOV_208_070_163_Live.fcs · VaccTranspl_ST2_20211216_TP_ICOV_234_071_164_Live.fcs · VaccTranspl_ST2_20211216_TP_ICOV_237_072_165_Live.fcs · VaccTranspl_ST2_20211216_TP_ICOV_431_064_157_Live.fcs · VaccTranspl_ST2_20211216_TP_ICOV_456_066_159_Live.fcs |
| Conditions | |
|---|---|
| · Dose 2 responder | Samples_Kidney_Tx_n_044_004_live cells.fcs · Samples_Kidney_Tx_n_045_005_live cells.fcs · Samples_Kidney_Tx_n_052_009_live cells.fcs · Samples_Kidney_Tx_n_053_010_live cells.fcs · Samples_Kidney_Tx_n_077_015_live cells.fcs · Samples_Lung_049_D1_D0_023_live cells.fcs · Samples_Lung_051_D1_D0_025_live cells.fcs · Samples_Lung_053_D1_D0_026_live cells.fcs · Samples_Lung_054_D1_D0_027_live cells.fcs · Samples_Lung_058_D1_D0_030_live cells.fcs · Samples_Lung_060_D1_D0_032_live cells.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_042_002_002_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_044_004_004_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_045_005_005_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_047_006_006_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_052_009_009_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_053_010_010_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_065_012_012_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_066_021_021_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_075_014_014_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_075_015_015_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_049_D1D0_023_023_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_051_D1D0_025_025_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_053_D1D0_026_026_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_054_D1D0_027_027_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_058_D1D0_030_030_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_060_D1D0_032_032_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_017_021_114_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_025_030_123_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_030_006_099_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_033_008_101_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_034_009_102_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_035_010_103_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_040_013_106_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_199_031_124_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_017_D1D0_043_136_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_019_D1D0_045_138_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_022_D1D0_048_141_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_030_D1D0_056_149_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_037_036_129_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_038_012_105_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_051_014_107_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_054_015_108_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_071_002_095_Live.fcs |
| · Dose 2 non-responder | Samples_Kidney_Tx_n_011_016_live cells.fcs · Samples_Kidney_Tx_n_043_003_live cells.fcs · Samples_Kidney_Tx_n_050_008_live cells.fcs · Samples_Kidney_Tx_n_061_019_live cells.fcs · Samples_Kidney_Tx_n_067_022_live cells.fcs · Samples_Lung_050_D1_D0_024_live cells.fcs · Samples_Lung_055_D1_D0_028_live cells.fcs · Samples_Lung_056_D1_D0_029_live cells.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_011_016_016_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_043_003_003_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_049_007_007_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_059_018_018_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_061_019_019_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_066_022_022_Live.fcs · VaccTranspl_ST2_20211210_TP_Kidney_Tx_n_073_013_013_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_050_D1D0_024_024_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_055_D1D0_028_028_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_056_D1D0_029_029_Live.fcs · VaccTranspl_ST2_20211210_TP_Lung_059_D1D0_031_031_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_016_037_130_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_019_022_115_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_020_023_116_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_021_024_117_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_023_038_131_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_026_004_097_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_028_005_098_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_031_007_100_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_036_011_104_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_080_019_112_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_101_029_122_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_191_035_128_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_201_020_113_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_203_028_121_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_013_D1D0_039_132_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_014_D1D0_040_133_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_015_D1D0_041_134_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_016_D1D0_042_135_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_018_D1D0_044_137_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_020_D1D0_046_139_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_021_D1D0_047_140_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_023_D1D0_049_142_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_024_D1D0_050_143_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_025_D1D0_051_144_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_026_D1D0_052_145_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_027_D1D0_053_146_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_028_D1D0_054_147_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_029_D1D0_055_148_Live.fcs · VaccTranspl_ST2_20211216_TP_Lung_047_D1D0_059_152_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_039_026_119_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_058_027_120_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_060_003_096_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_063_033_126_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_068_001_094_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_069_034_127_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_074_016_109_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_078_017_110_Live.fcs · VaccTranspl_ST2_20211216_TP_Kidney_Tx_n_079_018_111_Live.fcs |
