Experiment Overview
| Repository ID: | FR-FCM-Z7A7 | Experiment name: | Diet-driven differential response of Akkermansia muciniphila modulates pathogen susceptibility | MIFlowCyt score: | 25.50% |
| Primary researcher: | Erica Grant | PI/manager: | Erica Grant | Uploaded by: | Erica Grant |
| Experiment dates: | 2017-08-01 - 2022-05-31 | Dataset uploaded: | Apr 2024 | Last updated: | Apr 2024 |
| Keywords: | [Dietary fiber] [Akkermansia] [Citrobacter] [gnotobiotic] | Manuscripts: | |||
| Organizations: |
Luxembourg Institute of Health, Luxembourg, (Luxembourg)
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| Purpose: | Characterize immune profiles of mice colonized with a 13-member synthetic human gut microbiome (13SM, lacking Akkermansia muciniphila) or 14SM (with A. muciniphila) and fed a fiber-rich or fiber-free diet for 40 days prior to infection with murine enteropathogen Citrobacter rodentium. Immune cells were extracted from colonic lamina propria at 3 days post infection. | ||||
| Conclusion: | None | ||||
| Comments: | SAMPLE METADATA Filename ID SM Diet Tcells_samples_A6_Colon_1-R1.fcs E1R1 13SM FR Tcells_samples_B6_Colon_1-R2.fcs E1R2 13SM FR Tcells_samples_C6_Colon_1-L1.fcs E1L1 13SM FR Tcells_samples_D6_Colon_2-R1.fcs E2R1 13SM FR Tcells_samples_E6_Colon_2-NM.fcs E2NM 13SM FR Tcells_samples_F6_Colon_3-R1.fcs E3R1 13SM FF Tcells_samples_G6_Colon_3-R2.fcs E3R2 13SM FF Tcells_samples_H6_Colon_3-NM.fcs E3NM 13SM FF Tcells_samples_A7_Colon_4-R1.fcs E4R1 13SM FF Tcells_samples_B7_Colon_4-NM.fcs E4NM 13SM FF Tcells_samples_C7_Colon_5-R1.fcs E5R1 14SM FR Tcells_samples_D7_Colon_5-R2.fcs E5R2 14SM FR Tcells_samples_E7_Colon_5-L1.fcs E5L1 14SM FR Tcells_samples_F7_Colon_5-NM.fcs E5NM 14SM FR Tcells_samples_G7_Colon_6-R1.fcs E6R1 14SM FR Tcells_samples_H7_Colon_6-NM.fcs E6NM 14SM FR Tcells_samples_A8_Colon_7-R1.fcs E7R1 14SM FF Tcells_samples_B8_Colon_7-R2.fcs E7R2 14SM FF Tcells_samples_C8_Colon_7-L1.fcs E7L1 14SM FF Tcells_samples_D8_Colon_7-NM.fcs E7NM 14SM FF Tcells_samples_E8_Colon_8-R1.fcs E8R1 14SM FF Tcells_samples_F8_Colon_8-R1L1.fcs E8NM 14SM FF | ||||
| Funding: | Not disclosed | ||||
| Quality control: | None | ||||
Experiment variables
| Sample Type | |
|---|---|
| · 13SM FF | Tcells_samples_A7_Colon_4-R1.fcs · Tcells_samples_B7_Colon_4-NM.fcs · Tcells_samples_D7_Colon_5-R2.fcs · Tcells_samples_E7_Colon_5-L1.fcs · Tcells_samples_F6_Colon_3-R1.fcs · Tcells_samples_H6_Colon_3-NM.fcs |
| · 13SM FR | Tcells_samples_A6_Colon_1-R1.fcs · Tcells_samples_B6_Colon_1-R2.fcs · Tcells_samples_C6_Colon_1-L1.fcs · Tcells_samples_D6_Colon_2-R1.fcs · Tcells_samples_E6_Colon_2-NM.fcs · Tcells_samples_G6_Colon_3-R2.fcs |
| · 14SM FF | Tcells_samples_A8_Colon_7-R1.fcs · Tcells_samples_B8_Colon_7-R2.fcs · Tcells_samples_C8_Colon_7-L1.fcs · Tcells_samples_D8_Colon_7-NM.fcs · Tcells_samples_E8_Colon_8-R1.fcs · Tcells_samples_F8_Colon_8-R1L1.fcs |
| · 14SM FR | Tcells_samples_C7_Colon_5-R1.fcs · Tcells_samples_F7_Colon_5-NM.fcs · Tcells_samples_G7_Colon_6-R1.fcs · Tcells_samples_H7_Colon_6-NM.fcs |
