Experiment Overview
| Repository ID: | FR-FCM-ZY6A | Experiment name: | B16BL6 Checkpoint blockade | MIFlowCyt score: | 49.25% |
| Primary researcher: | Spencer Wei | PI/manager: | Spencer Wei | Uploaded by: | Spencer Wei |
| Experiment dates: | 2017-05-02 - | Dataset uploaded: | May 2017 | Last updated: | Aug 2017 |
| Keywords: | [mass cytometry] [CyTOF] [melanoma] [PD-1] [CTLA-4] [checkpoint blockade] [murine tumor model] [B16] | Manuscripts: | |||
| Organizations: |
The University of Texas MD Anderson Cancer Center, Immunology, Houston, Texas (USA)
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| Purpose: | To comprehensively B16BL6 tumor infiltrating T cell populations and to identify checkpoint blockade responsive T cell subsets using mass cytometry. | ||||
| Conclusion: | None | ||||
| Comments: | TIL mass cytometry data from individual mice from three independent cohorts. Samples were barcoded within each experiment. | ||||
| Funding: | Not disclosed | ||||
| Quality control: | Samples were omitted from downstream analyses if there were not sufficient T cell events for analysis (see methods section of manuscript). | ||||
Experiment variables
| Conditions | |
|---|---|
| · Control + GVAX | c01_2016-0930-B16BL6-TIL_norm.fcs · c02_2016-0930-B16BL6-TIL_norm.fcs · c03_2016-0930-B16BL6-TIL_norm.fcs · c04_2016-0930-B16BL6-TIL_norm.fcs · c05_2016-0930-B16BL6-TIL_norm.fcs · c06_2016-0930-B16BL6-TIL_norm.fcs · c07_2016-0930-B16BL6-TIL_norm.fcs · c01_2016-0722-BL6-GVAX_norm.fcs · c02_2016-0722-BL6-GVAX_norm.fcs · c03_2016-0722-BL6-GVAX_norm.fcs · c04_2016-0722-BL6-GVAX_norm.fcs · c05_2016-0722-BL6-GVAX_norm.fcs · c01_C147-C166.fcs · c02_C147-C166.fcs · c03_C147-C166.fcs · c04_C147-C166.fcs · c05_C147-C166.fcs · c06_C147-C166.fcs |
| · aCTLA-4 + GVAX | c08_2016-0930-B16BL6-TIL_norm.fcs · c09_2016-0930-B16BL6-TIL_norm.fcs · c10_2016-0930-B16BL6-TIL_norm.fcs · c11_2016-0930-B16BL6-TIL_norm.fcs · c12_2016-0930-B16BL6-TIL_norm.fcs · c13_2016-0930-B16BL6-TIL_norm.fcs · c09_2016-0722-BL6-GVAX_norm.fcs · c10_2016-0722-BL6-GVAX_norm.fcs · c11_2016-0722-BL6-GVAX_norm.fcs · c12_2016-0722-BL6-GVAX_norm.fcs · c13_2016-0722-BL6-GVAX_norm.fcs · c14_2016-0722-BL6-GVAX_norm.fcs · c07_C147-C166.fcs · c08_C147-C166.fcs · c09_C147-C166.fcs · c10_C147-C166.fcs · c11_C147-C166.fcs · c12_C147-C166.fcs · c13_C147-C166.fcs |
| · aPD-1 + GVAX | c14_2016-0930-B16BL6-TIL_norm.fcs · c15_2016-0930-B16BL6-TIL_norm.fcs · c16_2016-0930-B16BL6-TIL_norm.fcs · c17_2016-0930-B16BL6-TIL_norm.fcs · c18_2016-0930-B16BL6-TIL_norm.fcs · c19_2016-0930-B16BL6-TIL_norm.fcs · c20_2016-0930-B16BL6-TIL_norm.fcs · c15_2016-0722-BL6-GVAX_norm.fcs · c17_2016-0722-BL6-GVAX_norm.fcs · c18_2016-0722-BL6-GVAX_norm.fcs · c20_2016-0722-BL6-GVAX_norm.fcs · c15_C147-C166.fcs · c16_C147-C166.fcs · c17_C147-C166.fcs · c18_C147-C166.fcs |
| Sample Type | |
|---|---|
| · Cohort 1 | c01_C147-C166.fcs · c02_C147-C166.fcs · c03_C147-C166.fcs · c04_C147-C166.fcs · c05_C147-C166.fcs · c06_C147-C166.fcs · c07_C147-C166.fcs · c08_C147-C166.fcs · c09_C147-C166.fcs · c10_C147-C166.fcs · c11_C147-C166.fcs · c12_C147-C166.fcs · c13_C147-C166.fcs · c15_C147-C166.fcs · c16_C147-C166.fcs · c17_C147-C166.fcs · c18_C147-C166.fcs |
| · Cohort 2 | c01_2016-0722-BL6-GVAX_norm.fcs · c02_2016-0722-BL6-GVAX_norm.fcs · c03_2016-0722-BL6-GVAX_norm.fcs · c04_2016-0722-BL6-GVAX_norm.fcs · c05_2016-0722-BL6-GVAX_norm.fcs · c09_2016-0722-BL6-GVAX_norm.fcs · c10_2016-0722-BL6-GVAX_norm.fcs · c11_2016-0722-BL6-GVAX_norm.fcs · c12_2016-0722-BL6-GVAX_norm.fcs · c13_2016-0722-BL6-GVAX_norm.fcs · c14_2016-0722-BL6-GVAX_norm.fcs · c15_2016-0722-BL6-GVAX_norm.fcs · c17_2016-0722-BL6-GVAX_norm.fcs · c18_2016-0722-BL6-GVAX_norm.fcs · c20_2016-0722-BL6-GVAX_norm.fcs |
| · Cohort 3 | c01_2016-0930-B16BL6-TIL_norm.fcs · c02_2016-0930-B16BL6-TIL_norm.fcs · c03_2016-0930-B16BL6-TIL_norm.fcs · c04_2016-0930-B16BL6-TIL_norm.fcs · c05_2016-0930-B16BL6-TIL_norm.fcs · c06_2016-0930-B16BL6-TIL_norm.fcs · c07_2016-0930-B16BL6-TIL_norm.fcs · c08_2016-0930-B16BL6-TIL_norm.fcs · c09_2016-0930-B16BL6-TIL_norm.fcs · c10_2016-0930-B16BL6-TIL_norm.fcs · c11_2016-0930-B16BL6-TIL_norm.fcs · c12_2016-0930-B16BL6-TIL_norm.fcs · c13_2016-0930-B16BL6-TIL_norm.fcs · c14_2016-0930-B16BL6-TIL_norm.fcs · c15_2016-0930-B16BL6-TIL_norm.fcs · c16_2016-0930-B16BL6-TIL_norm.fcs · c17_2016-0930-B16BL6-TIL_norm.fcs · c18_2016-0930-B16BL6-TIL_norm.fcs · c19_2016-0930-B16BL6-TIL_norm.fcs · c20_2016-0930-B16BL6-TIL_norm.fcs |
