Experiment Overview
| Repository ID: | FR-FCM-ZY9F | Experiment name: | SLAMF Immunophenotype in SLE | MIFlowCyt score: | 92.06% |
| Primary researcher: | Maria Karampetsou | PI/manager: | George Tsokos | Uploaded by: | Maria Karampetsou |
| Experiment dates: | 2014-02-03 - 2015-10-20 | Dataset uploaded: | Aug 2017 | Last updated: | Apr 2024 |
| Keywords: | [SLE] [autoimmunity] [SLAMF] | Manuscripts: | |||
| Organizations: |
Beth Israel Deaconess Medical Center, Harvard Medical School, Division of Rheumatology, Boston, Massachusetts (United States)
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| Purpose: | To examine the expression of SLAMF1-7 on peripheral blood T cells, B cells, monocytes, and their respective differentiated subsets, in patients with SLE and healthy controls in a systematic manner. | ||||
| Conclusion: | The expression of various SLAMF receptors is dysregulated in patients with systemic lupus erythematosus and may contribute to the immunopathogenesis of the disease. | ||||
| Comments: | None | ||||
| Funding: | NIH grants PO1 AI065687, RO1 AI42269 and R37 AI49954 (to G.C.T.). This work was also supported by a SICPA foundation grant (to D.C.). | ||||
| Quality control: | None | ||||
