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Experiment Overview

Repository ID: FR-FCM-ZY9X Experiment name: Spontaneous cytokine production from paired blood, tumor and non-involved lung from NSCLC patients MIFlowCyt score: 62.00%
Primary researcher: Adeeb Rahman PI/manager: Adeeb Rahman Uploaded by: Adeeb Rahman
Experiment dates: 2016-02-09 - 2016-06-10 Dataset uploaded: Aug 2017 Last updated: Aug 2017
Keywords: [Intracellular Cytokine Staining] [mass cytometry] [CyTOF] [NSCLC] Manuscripts: [28475900]
Organizations: Icahn School of Medicine at Mount Sinai , New York, NY (United States of America)
Purpose: To characterize spontaneous cytokine production from immune populations from paired blood, tumor and non-involved lung tissue from NSCLC patients
Conclusion: None
Comments: Single cell suspensions from blood, tumor and lung were incubated for 4-6hrs in Brefeldin A. Samples were stained for viability and surface markers, and matched sets of samples from a single patient were then fixed and barcoded using the Fluidigm Pd barcoding kit and pooled prior to intracellular staining for cytokines. Data were normalized and debarcoded using Fluidigm software.
Funding: Not disclosed
Quality control: None


Experiment variables

Individuals
· 301 lung_cytokine_301_Blood_BFA_live.fcs · lung_cytokine_301_Lung_BFA_live.fcs · lung_cytokine_301_Tumor_BFA_live.fcs
· 305 lung_cytokine_305_Blood_BFA_live.fcs · lung_cytokine_305_Lung_BFA_live.fcs · lung_cytokine_305_Tumor_BFA_live.fcs
· 312 lung_cytokine_312_Blood_BFA_live.fcs · lung_cytokine_312_Lung_BFA_live.fcs · lung_cytokine_312_Tumor_BFA_live.fcs
· 315 lung_cytokine_315_Blood_BFA_live.fcs · lung_cytokine_315_Lung_BFA_live.fcs · lung_cytokine_315_Tumor_BFA_live.fcs
· 324 lung_cytokine_324_Blood_BFA_live.fcs · lung_cytokine_324_Lung_BFA_live.fcs · lung_cytokine_324_Tumor_BFA_live.fcs
· 326 lung_cytokine_326_Blood_BFA_live.fcs · lung_cytokine_326_Lung_BFA_live.fcs · lung_cytokine_326_Tumor_BFA_live.fcs
· 327 lung_cytokine_327_Blood_BFA_live.fcs · lung_cytokine_327_Lung_BFA_live.fcs · lung_cytokine_327_Tumor_BFA_live.fcs
· 328 lung_cytokine_328_Blood_BFA_live.fcs · lung_cytokine_328_Lung_BFA_live.fcs · lung_cytokine_328_Tumor_BFA_live.fcs
· 329 lung_cytokine_329_Blood_BFA_live.fcs · lung_cytokine_329_Lung_BFA_live.fcs · lung_cytokine_329_Tumor_BFA_live.fcs

Sample Type
· blood lung_cytokine_301_Blood_BFA_live.fcs · lung_cytokine_305_Blood_BFA_live.fcs · lung_cytokine_312_Blood_BFA_live.fcs · lung_cytokine_315_Blood_BFA_live.fcs · lung_cytokine_324_Blood_BFA_live.fcs · lung_cytokine_326_Blood_BFA_live.fcs · lung_cytokine_327_Blood_BFA_live.fcs · lung_cytokine_328_Blood_BFA_live.fcs · lung_cytokine_329_Blood_BFA_live.fcs
· lung lung_cytokine_301_Lung_BFA_live.fcs · lung_cytokine_305_Lung_BFA_live.fcs · lung_cytokine_312_Lung_BFA_live.fcs · lung_cytokine_315_Lung_BFA_live.fcs · lung_cytokine_324_Lung_BFA_live.fcs · lung_cytokine_326_Lung_BFA_live.fcs · lung_cytokine_327_Lung_BFA_live.fcs · lung_cytokine_328_Lung_BFA_live.fcs · lung_cytokine_329_Lung_BFA_live.fcs
· tumor lung_cytokine_301_Tumor_BFA_live.fcs · lung_cytokine_305_Tumor_BFA_live.fcs · lung_cytokine_312_Tumor_BFA_live.fcs · lung_cytokine_315_Tumor_BFA_live.fcs · lung_cytokine_324_Tumor_BFA_live.fcs · lung_cytokine_326_Tumor_BFA_live.fcs · lung_cytokine_327_Tumor_BFA_live.fcs · lung_cytokine_328_Tumor_BFA_live.fcs · lung_cytokine_329_Tumor_BFA_live.fcs

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