Experiment Overview
| Repository ID: | FR-FCM-ZYDG | Experiment name: | Mass Cytometry of Peripheral Blood from Melanoma Patients Receiving anti-PD-1 | MIFlowCyt score: | 53.75% |
| Primary researcher: | Allison Greenplate | PI/manager: | Jonathan Irish | Uploaded by: | Allison Greenplate |
| Experiment dates: | 2015-08-01 - 2017-08-01 | Dataset uploaded: | Nov 2017 | Last updated: | Oct 2018 |
| Keywords: | [human PBMC] [mass cytometry] [melanoma] [immunotherapy] | Manuscripts: | [30413431] |
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| Organizations: |
Vanderbilt University School of Medicine, Pathology, Microbiology, and Immunology, Nashville, TN (USA)
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| Purpose: | The purpose was to monitor peripheral changes in the immune systems of melanoma patients receiving anti-PD-1 therapy. | ||||
| Conclusion: | The major immune populations found in the peripheral blood of melanoma patients remain stable over the course of therapy. | ||||
| Comments: | Patient MB-009 was featured in a case report in Cancer Immunology Research (Greenplate, et al 2016). | ||||
| Funding: | Not disclosed | ||||
| Quality control: | Fluidigm normalization beads were used. Beads have been left in the FCS files. | ||||
Experiment variables
| Sample Type | |
|---|---|
| · Healthy PBMC | VU10_PBMC.fcs · VU14_PBMC.fcs · VU17_PBMC.fcs · VU18_PBMC.fcs · VUK006_PBMC.fcs · VUK007_PBMC.fcs · VUK008_PBMC.fcs |
| · melanoma PBMC | MB004_12wk_PBMC.fcs · MB004_3wk_PBMC.fcs · MB004_6m_PBMC.fcs · MB004_pre_PBMC.fcs · MB005_12wk_PBMC.fcs · MB005_3wk_PBMC.fcs · MB005_6m_PBMC.fcs · MB005_pre_PBMC.fcs · MB006_12wk_PBMC.fcs · MB006_5wk_PBMC.fcs · MB006_6m_PBMC.fcs · MB006_pre_PBMC.fcs · MB007_3wk_PBMC.fcs · MB007_pre_PBMC.fcs · MB008_12wk_PBMC.fcs · MB008_3wk_PBMC.fcs · MB008_6m_PBMC.fcs · MB008_pre_PBMC.fcs · MB009_12wk_PBMC.fcs · MB009_3wk_PBMC.fcs · MB009_6m_PBMC.fcs · MB009_pre_PBMC.fcs · MB010_12wk_PBMC.fcs · MB010_3wk_PBMC.fcs · MB010_6m_PBMC.fcs · MB010_pre_PBMC.fcs · MB012_12wk_PBMC.fcs · MB012_3wk_PBMC.fcs · MB012_6m_PBMC.fcs · MB012_pre_PBMC.fcs · MB013_6m_PBMC.fcs · MB013_6wk_PBMC.fcs · MB013_pre_PBMC.fcs · MB041_3wk_PBMC.fcs · MB041_pre_PBMC.fcs |
| · iPCS | iPSCs_Pembro.fcs |
| Individuals | |
|---|---|
| · MB004 | MB004_12wk_PBMC.fcs · MB004_3wk_PBMC.fcs · MB004_6m_PBMC.fcs · MB004_pre_PBMC.fcs |
| · MB005 | MB005_12wk_PBMC.fcs · MB005_3wk_PBMC.fcs · MB005_6m_PBMC.fcs · MB005_pre_PBMC.fcs |
| · MB006 | MB006_12wk_PBMC.fcs · MB006_5wk_PBMC.fcs · MB006_6m_PBMC.fcs · MB006_pre_PBMC.fcs |
| · MB007 | MB007_3wk_PBMC.fcs · MB007_pre_PBMC.fcs |
| · MB008 | MB008_12wk_PBMC.fcs · MB008_3wk_PBMC.fcs · MB008_6m_PBMC.fcs · MB008_pre_PBMC.fcs |
| · MB009 | MB009_12wk_PBMC.fcs · MB009_3wk_PBMC.fcs · MB009_6m_PBMC.fcs · MB009_pre_PBMC.fcs |
| · MB010 | MB010_12wk_PBMC.fcs · MB010_3wk_PBMC.fcs · MB010_6m_PBMC.fcs · MB010_pre_PBMC.fcs |
| · MB012 | MB012_12wk_PBMC.fcs · MB012_3wk_PBMC.fcs · MB012_6m_PBMC.fcs · MB012_pre_PBMC.fcs |
| · MB013 | MB013_6m_PBMC.fcs · MB013_6wk_PBMC.fcs · MB013_pre_PBMC.fcs |
| · MB041 | MB041_3wk_PBMC.fcs · MB041_pre_PBMC.fcs |
