Experiment Overview
| Repository ID: | FR-FCM-ZYFR | Experiment name: | Ctla-4 Immunization | MIFlowCyt score: | 15.00% |
| Primary researcher: | Spencer Wei | PI/manager: | Spencer Wei | Uploaded by: | Spencer Wei |
| Experiment dates: | 2016-12-01 - | Dataset uploaded: | Jan 2018 | Last updated: | Jul 2019 |
| Keywords: | None | Manuscripts: | |||
| Organizations: | None | ||||
| Purpose: | The purpose of these experiments was to determine whether expansion in the observed T cell phenotypes in Ctla-4 knockout mice were due to uncontrolled proliferation. To address this possibility, Ctla-4 knockout mice and littermate control mice were randomized to unimmunized or immunized groups (Ova in CFA) and analyzed using mass cytometry panels designed to deeply interrogate T cell activation status and differentiation. | ||||
| Conclusion: | None | ||||
| Comments: | DOI:https://doi.org/10.1016/j.immuni.2019.03.004 Mouse ID Genotype Note D117 Het Non-imm D118 WT Immunized D119 WT Non-imm D120 WT Immunized D122 WT Immunized D123 WT Non-imm D124 KO Non-imm D125 Het Immunized D126 KO Immunized D127 KO Non-imm D128 Het Non-imm D129 WT Immunized D130 WT Non-imm D131 Het Non-imm D132 WT Immunized D133 KO Non-imm D134 KO Non-imm D135 KO Immunized D136 Het Non-imm D137 Het Immunized | ||||
| Funding: | Not disclosed | ||||
| Quality control: | None | ||||
