Experiment Overview
| Repository ID: | FR-FCM-ZYWH | Experiment name: | Huse et al Cytometry A 2018 Figure 4 (exp 2) | MIFlowCyt score: | 23.25% |
| Primary researcher: | Kanutte Huse | PI/manager: | June Helen Myklebust | Uploaded by: | Kanutte Huse |
| Experiment dates: | 2015-03-11 - | Dataset uploaded: | Apr 2018 | Last updated: | Mar 2019 |
| Keywords: | [CD40 signaling] [germinal center B cell] | Manuscripts: | [30838773] |
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| Organizations: |
Oslo University Hospital, Oslo, (Norway)
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| Purpose: | To quantifying CD40 signaling responses as a function of bound ligand in GC and non-GC B cells | ||||
| Conclusion: | We found a correlation between bound CD40L and degree of induced NFκB p65 phosphorylation, whereas comparable IκBα degradation occurred at all measured levels of CD40L binding. | ||||
| Comments: | None | ||||
| Funding: | This study was supported by NIH/NCI R00 CA143231-03 (J.M.I. and C.E.W.) and R25 CA136440-04 (K.E.D.), The Norwegian Cancer Society (K.H.), the Centre for Cancer Biomedicine, the Vanderbilt-Ingram Cancer Center (VICC, P30 CA68485), and VICC Ambassadors and Hematology Helping Hand Fund awards. | ||||
| Quality control: | None | ||||
