Experiment Overview
| Repository ID: | FR-FCM-ZZ8L | Experiment name: | Different calcium influx characteristics upon Kv1.3 and IKCa1 potassium channel inhibition in T helper subsets | MIFlowCyt score: | 24.00% |
| Primary researcher: | Csaba Orbán | PI/manager: | Csaba Orbán | Uploaded by: | Csaba Orbán |
| Experiment dates: | 2012-02-08 - 2012-06-09 | Dataset uploaded: | Nov 2013 | Last updated: | May 2014 |
| Keywords: | None | Manuscripts: | [24827427] |
|
|
| Organizations: |
Semmelweis University, First Pediatrics, Budapest, (Hungary)
|
||||
| Purpose: | We aimed to investigate calcium influx sensitivity to the inhibition of potassium channels in the main T helper subsets. | ||||
| Conclusion: | Upon the inhibition of IKCa1 channels, short-term activation of pro-inflammatory cells was specifically decreased without affecting anti-inflammatory subsets, indicating that selective immunomodulation is possible in healthy individuals. | ||||
| Comments: | None | ||||
| Funding: | Not disclosed | ||||
| Quality control: | None | ||||
