Experiment Overview
| Repository ID: | FR-FCM-ZZA9 | Experiment name: | Effects of CYP1A1 Inhibition | MIFlowCyt score: | 77.18% |
| Primary researcher: | Margaret Lowe | PI/manager: | Margaret Lowe | Uploaded by: | Margaret Lowe |
| Experiment dates: | 2012-08-15 - 2012-09-06 | Dataset uploaded: | Mar 2014 | Last updated: | Aug 2014 |
| Keywords: | [IL17; IL22; mouse; T cells] | Manuscripts: | [24498387] [PMC3912126] |
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| Organizations: |
University of California, San Francisco, San Francisco, CA (United States)
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| Purpose: | To determine whether CYP1A1 inhibition affects IL-22 production in mouse CD4 T cells differentiated under polarizing conditions | ||||
| Conclusion: | Inhibition of CYP1A1 with 1-PP does not affect IL-22 production in mouse CD4 T cells | ||||
| Comments: | See Figure 8G in Lowe et al PLOS One 2014 | ||||
| Funding: | Not disclosed | ||||
| Quality control: | None | ||||
Experiment variables
| Conditions | |
|---|---|
| · CA 10 µM | 0815 samples gamma_CA 10.fcs · 0829_CA 10.fcs · 0831_CA 10.fcs |
| · DMSO 25 µM equivalent | 0815 samples gamma_DMSO.fcs · 0829_DMSO.fcs · 0831_DMSO.fcs |
| · CA 25 µM | 0815 samples gamma_CA 25.fcs · 0829_CA 25.fcs · 0831_CA 25.fcs |
| · 1-PP 1 µM | 0815 samples gamma_1PP 1.fcs · 0829_1PP 1.fcs · 0831_1PP 1.fcs |
| · 1-PP 10 µM | 0815 samples gamma_1 PP 10.fcs · 0829_1 PP 10.fcs · 0831_1 PP 10.fcs |
| · 1-PP 1 µM + CA 10 µM | 0815 samples gamma_1PP 1 CA 10.fcs · 0829_1PP 1 CA 10.fcs · 0831_1PP 1 CA 10.fcs |
| · 1-PP 10 µM + CA 10 µM | 0815 samples gamma_1PP 10 CA 10.fcs · 0829_1PP 10 CA 10.fcs · 0831_1PP 10 CA 10.fcs |
