Experiment Overview
| Repository ID: | FR-FCM-Z7KP | Experiment name: | Anti-inflammatory role of low intensity pulsed ultrasound in inhibiting LPS-induced M1 polarization of RAW264.7 | MIFlowCyt score: | 27.00% |
| Primary researcher: | Juan Yin | PI/manager: | Juan Yin | Uploaded by: | Juan Yin |
| Experiment dates: | 2022-01-03 - | Dataset uploaded: | May 2024 | Last updated: | May 2024 |
| Keywords: | [low intensity pulsed ultrasound] [M1 polarization] [RAW264.7] [Wnt2b ] | Manuscripts: | |||
| Organizations: |
Nanjing Medical University, Central Laboratory, Suzhou Municipal Hospital, The Aûliated Suzhou Hospital of Nanjing Medical University, Gusu Schoo, Suzhou, Jiangsu (China)
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| Purpose: | To study the specific mechanism of LIPUS in the treatment of periodontal disease. | ||||
| Conclusion: | LIPUS played an anti-inûammatory role by inhibiting LPS-induced M1 polarization of RAW264.7 in an Wnt2b/AXIN/β-catenin dependent way. LIPUS may inhibit inûammation in periodontal diseases by regulating macrophage diûerentiation, so as to play a therapeutic role in periodontal diseases. | ||||
| Comments: | None | ||||
| Funding: | This work was supported by the Program of Jiangsu science and technology Department (BK20211083,BE2022737), the Program of Suzhou Health Commission (GSWS2020078, SZXK202111), the Program of Suzhou science and technology Department (SKY2023062, SKJY2021123). | ||||
| Quality control: | None | ||||
