
Experiment Overview
Repository ID: | FR-FCM-Z5DS | Experiment name: | ALKBH5 overexpression blocks the 2,4-PDCA-induced cell apoptosis in UM-SCC-1 cells | MIFlowCyt score: | 39.50% |
Primary researcher: | Zhijian Qian | PI/manager: | Zhijian Qian | Uploaded by: | Zhijian Qian |
Experiment dates: | 2021-01-06 - 2021-01-06 | Dataset uploaded: | May 2022 | Last updated: | May 2022 |
Keywords: | None | Manuscripts: | |||
Organizations: | None | ||||
Purpose: | To determine whether 2,4-PDCA-induced UM-SCC-1 cell apoptosis is caused by off-target effect. | ||||
Conclusion: | 2,4-PDCA-induced UM-SCC-1 cell apoptosis can only be rescued by wild-type ALKBH5 but not the ALKBH5 enzymatic mutant, suggesting that 2,4-PDCA-induced UM-SCC-1 cell apoptosis is via ALKBH5. | ||||
Comments: | None | ||||
Funding: | Not disclosed | ||||
Quality control: | None |